Antibiotic optimization. An evaluation of patient safety and economic outcomes
49% of intervention group received suggestions. Per patient antibiotics cost was $400 lower in intervention vs. control (p=0.05). Clinical outcomes similar for patients in both groups.
Reference:
Fraser GL, Stogsdill P, Dickens JD, Wennberg DE, Smith RP, and Prato BS. An evaluation of patient safety and economic outcomes. Archives of Internal Medicine. 1997; 157: 1689-1694
Setting:
600-bed, tertiary-care teaching hospital, Portland, ME, USA
Key staff:
infectious disease physician and clinical pharmacist
Intervention:
Multidisciplinary – Three month randomized controlled trial of patients receiving parenteral antibiotics for three or more consecutive days. Intervention group received suggestion for antibiotics from ID and pharmacist. The control did not.
Impact:
49% of intervention group received suggestions. Per patient antibiotics cost was $400 lower in intervention vs. control (p=0.05). Clinical outcomes similar for patients in both groups.