A randomized, prospective study measuring outcomes after antibiotic therapy intervention by a multidisciplinary consult team.

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Median length of stay after randomization for control and intervention groups was 9.0 days and 5.7 days, respectively (3.3-day difference, p=0.0001). Physician acceptance of suggestions was 89%. Median patient charges for radiology, laboratory, pharmacy, and room were reduced by $4,404/intervention, and median hospital costs were reduced by $2,642/intervention.

Reference:
Gums JG, Tancey Jr RW, Hamilton CA, Kubilis PS. A randomized, prospective study measuring outcomes after antibiotic therapy intervention by a multidisciplinary consult team.  Pharmacotherapy 1999; (19):1369-1377

Setting:
275-bed, community teaching hospital, Gainesville, FL, USA

Key staff:
ID physician, clinical pharmacy fellow and micro lab personnel

Resources Required:
Part-time work for all members of multidisciplinary team

Intervention:
Patients with known resistant infections randomized to an intervention consult vs. usual care.  Interventional consult done by multidisciplinary team and made recommendations for appropriate therapies while also weighing economic factors of medication.

Impact:
Median length of stay after randomization for control and intervention groups was 9.0 days and 5.7 days, respectively (3.3-day difference, p=0.0001). Physician acceptance of suggestions was 89%. Median patient charges for radiology, laboratory, pharmacy, and room were reduced by $4,404/intervention, and median hospital costs were reduced by $2,642/intervention.

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Antibiotic Combinations with Redundant Antimicrobial Spectra: Clinical Epidemiology and Pilot Intervention of Computer-Assisted Surveillance

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Antimicrobial Stewardship (ASP) in Rural and Critical Access Hospitals (CAHs) Using TeleStewardship® Services