Antibiotic Combinations with Redundant Antimicrobial Spectra: Clinical Epidemiology and Pilot Intervention of Computer-Assisted Surveillance

Antibiotic Optimization
Written By Adventure Administrator
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71% of combinations investigated found to be inappropriate. Intervention projected to have $10,800 in cost savings and 584-day reduction in antibiotic combination days.

Reference:
Glowacki RC, Schwartz DN, Itokazu GS, Wisniewski MF, Kieszkowski P, Weinstein RA. Antibiotic Combinations with Redundant Antimicrobial Spectra: Clinical Epidemiology and Pilot Intervention of Computer-Assisted Surveillance. CID. 2003 (37): 59-64

Setting:
600-bed, public teaching hospital, Chicago, IL, USA

Key staff:
Infectious disease pharmacist

Resources Required:
$2880 for pharmacist’s time

Intervention:
Streamlining – Patients on two or more antibiotics identified by computer. After records review for redundant combinations, pharmacist would contact clinician to determine clinical indication and make recommendations for streamlining when appropriate.

Impact:
71% of combinations investigated found to be inappropriate. Intervention projected to have $10,800 in cost savings and 584-day reduction in antibiotic combination days.

Tools:
Inpatient pharmacy computer system for identifying patients on >=2 antibiotics


Adventure Administrator

Adventure Studios was established in 2006 as a design and development firm offering an alternative to the typical models of executive software services available, including 100% custom construction, an expensive and time-intensive process, or the “one-size-fits-all” services that either lack necessary features or are encumbered by too many.

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Antibiotic tele-stewardship program reduces antibiotic use, improving patient outcomes
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A randomized, prospective study measuring outcomes after antibiotic therapy intervention by a multidisciplinary consult team.