Controlling cephalosporin and aminoglycoside costs through pharmacy and therapeutics committee restrictions

Return on Investment
Written By Adventure Administrator
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Second generation cephalosporin use decreased 52.2%, tobramycin decreased by 75.9% while unrestricted gentamicin increased 229% during study period. Reduced expenditures on injectable antibiotics by $193,172.06 during 12 months following restrictions.

Reference:
Hayman JN, Sbravati. Controlling cephalosporin and aminoglycoside costs through pharmacy and therapeutics committee restrictions. American Journal of Hospital Pharm. 1985; 42:1343-1347

Setting:
545-bed, state-supported, tertiary-care teaching hospital, Jackson, MS, USA

Key staff:
Pharmacy, Pharmacy and Therapeutics Committee

Intervention:
Guidelines – Established restrictions on use of 2nd generation cephalosporins and aminoglycosides requiring obtaining pharmacy approval before drug disbursement

Impact:
Second generation cephalosporin use decreased 52.2%, tobramycin decreased by 75.9% while unrestricted gentamicin increased 229% during study period.  Reduced expenditures on injectable antibiotics by $193,172.06 during 12 months following restrictions.


Adventure Administrator

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Antibiotic cost savings from formulary restrictions and physician monitoring in a medical-school-affiliated hospital
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Reduction in antibiotic costs by restricting use of an oral cephalosporin